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KMID : 0370020000140000049
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Chung-Ang Journal of Pharmacal Sciences
2000 Volume.14 No. 0 p.49 ~ p.54
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Synthesis of p-Aminosalicylic Thiourea Derivatives
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Abstract
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The nine new thiocarbailide derivatives of p-aminosalicylic acids were synthesized. Arylisothiocyanates were prepared by treatment of carbon disulfide, ammonia and aromatic amines. And alkyl p-aminosalicylates were synthesized by the reaction of p-aminosalicylic acid and alchols. The resulting alkyl p-aminosalicylates reacted with arylisothiocyanates to yield the thiocarbanilides.
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